Welcome to DRAGEN Array

DRAGEN (Dynamic Read Analysis for GENomics) Array secondary analysis is a powerful bioinformatics software for Illumina Infinium array-based assays. DRAGEN Array uses cutting-edge data analysis tools to provide accurate, comprehensive, and highly efficient secondary analysis to maximize genomic insights and meet your research needs across multiple applications.

DRAGEN Array is offered as a local package with command-line interface (no specialized server or hardware required) and as a cloud-based package with an intuitive graphical user interface, as summerized in the table below.

DescriptionKey featuresLocal analysisCloud analysis


Provides genotyping results for any human Infinium genotyping array.

  • Greater than 99.5% genotyping accuracy

  • Genotyping VCF in as little as 35 seconds per sample

PGx – CNV calling

Provides CNV calling on 6 target PGx genes across 9 target regions, plus genotyping outputs for Infinium microarrays with enhanced PGx content.

Greater than 95% PGx CNV accuracy

PGx – star allele annotation

Provides PGx star allele and variant coverage across 1700+ targets for over 50 genes, plus PGx CNV and genotyping outputs for Infinium microarrays with enhanced PGx content.

  • Assess hard to discern PGx genes, including the elusive CYP2D6 with greater than 98% call rate

  • Obtain all PGx analysis results in ~1 minute per sample

Methylation QC

Provides high-throughput, quantitative methylation quality control for Infinium methylation arrays.

  • 21 algorithm-based quantitative control metrics with adjustable thresholds

  • Data summary plots

  • Proportion of CG probes passing with user defined p-value threshold

This product documentation describes the installation and setup, analysis execution, and result outputs. For the latest updates and release details, see the DRAGEN Array Release Notes. See Introducing DRAGEN™ Array 1.0 for Infinium™ Array-Based Pharmacogenomics Analysis for additional details on DRAGEN Array genotyping, PGx CNV calling and PGx star allele annotation.

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For Research Use Only. Not for use in diagnostic procedures. © 2023 Illumina, Inc. All rights reserved.